The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
All tagged structural biology
The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.
The architectural details of a notorious cancer-promoting protein offer clues about how to keep it safely switched off.
Comprehensive mapping reveals dozens of sites on a single protein where small alterations change function.
Scientists’ CRISPR toolkit expands as researchers explore the natural diversity of bacterial immune systems.
Detailed pictures of the brain’s NMDA receptors will help guide the development of new treatments for psychiatric disorders.